NESA · Cardiology

Autonomic control of the heart — measurable.

NESA improves heart-rate variability and vagal tone — objective markers of autonomic control of the cardiovascular system.

Information for healthcare professionals

Self-recognition

Do you recognise yourself?

Heart rhythm and autonomic balance

✓palpitations or skipped beats
✓worse under stress or nerves
✓high resting heart rate
✓poor sleep and recovery
✓HRV measurement recommended
✓a sense of “gas” that won’t subside
What happens in the autonomic nervous system

Like a tuner showing — beat by beat — how balanced the nervous system is. Higher variability (HRV) means better balance and more autonomic reserve; interpretation is up to the specialist.

Self-assessment, not self-diagnosis — discuss with a professional.

Why NESA in cardiology

Precision and trust — through the autonomic balance of the heart.

01
01

Variability (HRV)

Increased heart-rate variability — a marker of healthy autonomic control.

02
02

Vagal tone

Strengthened parasympathetic (vagal) tone — linked to better cardiovascular health.

03
03

Stress & recovery

Reduced sympathetic stress — support for recovery and sleep quality.

How it works

Microcurrents that tune the vagus.

NESA applies controlled low-intensity (0.1–1 mA) low-frequency (1–15 Hz) microcurrents through eight electrodes on the four limbs and one guide electrode. The signal reaches the autonomic nervous system and restores the balance between its sympathetic and parasympathetic branches.

In cardiology this balance strengthens vagal (parasympathetic) tone and raises heart-rate variability (HRV) — validated markers of autonomic control and cardiovascular risk.

Intensity0.1–1 mA
Frequency1–15 Hz
Electrodes8 + 1 guide
MarkersHRV · vagal tone
Indications

Where NESA finds application in cardiology.

01Low heart-rate variability (HRV)
02Autonomic dysfunction (dysautonomia)
03Arterial hypertension — as a complement
04Cardiovascular rehabilitation
05Chronic stress and sympathetic overactivity
06Sleep disorders with cardiovascular risk
07Metabolic syndrome and internal medicine
08Recovery after a cardiac event
09Fatigue and reduced physical readiness
10Prevention and autonomic monitoring
Study results · heart-rate variability

NESA makes autonomic balance visible: HRV and vagal tone are measured objectively before and after the protocol.

HRV
An objective marker of autonomic balance — measured before and after the protocol with WeCardio.
≈ +29%
SDNN (30→39 ms) in the only HRV study — Melián-Ortíz 2025. Pilot, 16 women with post-COVID dysautonomia; both groups improved.
SDNN ≈ 50
ms — reference value for a healthy short-term record (RMSSD ≈ 42 ms); a guide.

NESA HRV study (Melián-Ortíz, Brain Sci. 2025): a randomised pilot in 16 women with post-COVID dysautonomia — SDNN and pain threshold improved significantly more with NESA; the authors recommend larger trials. An early, supportive signal. For healthcare professionals.

Protocol

A clear frame for the treatment course.

A typical course in cardiology. Parameters are adapted individually by the treating specialist and combined with ongoing therapy and monitoring.

12–20
sessions per course
2×
per week
55 min
per session
1–9
NESA programmes
For whom

Built for cardiology practice.

Cardiology clinics & wards

Centres seeking a non-invasive complement with objective autonomic markers.

Cardiac rehabilitation

Recovery after a cardiovascular event with HRV tracking.

Internal medicine & prevention

Metabolic risk, stress and autonomic dysregulation.

Downloadable materials

Full report — internal medicine and cardiology.

Indications, protocols, programmes and clinical data for implementing NESA in your practice.

PDF XSignal · reportBulgarian · Internal medicine & cardiology ↓ PDF XSignal in Internal Medicine & Cardiology — report (EN) ↓ PDFPatient cardFor patients · PDF (EN)↓
Frequently asked questions

Short answers for professionals.

Is the therapy safe?

Yes. NESA is a non-invasive, low-intensity method with no known systemic side effects. Sessions are conducted by a trained specialist.

Does it replace cardiology treatment?

No. NESA complements pharmacological treatment and rehabilitation by improving autonomic balance — within standard cardiology care.

How is the effect measured?

Objectively — via heart-rate variability (HRV) and vagal tone (RMSSD), tracked before and after the protocol.

Are there contraindications?

Pacemakers and other active electrical implants, pregnancy and epilepsy require prior medical assessment. When in doubt, consult the treating physician.

Related fields

Explore adjacent areas.

Поставяне на електроди на крайниците с NESA XSIGNAL®
Across the four limbs

Microcurrents through the wrists and ankles — the whole autonomic axis at once.

Protocol · 12–20 sessions · 2× weekly · 55 min

Bring NESA into cardiology care.

Request a demonstration →
Protocol parameters

Real values from the handbook (INF-CD-022)

Tachycardia and palpitations in anxiety

Sessionsmin. 20
FrequencyInduction → maintenance
Duration60 min (P7 45)
ProgrammesP1 · P2 · P4 · P7
Guiding electrodeSternum · C6–C7 · Processus spinosus T2–T4
QuestionnairesWeCardio · ECG · Holter

Quality of life in cardiology patients

Sessionsmin. 20
FrequencyInduction → maintenance
Duration60 min (P7 45)
ProgrammesP1 · P2 · P4 · P5 · P7
Guiding electrodeSternum · C6–C7 · T2–T4
QuestionnairesWeCardio · ECG · Holter

Source: NESA protocol handbook · INF-CD-022 (2025-V.1). Standard session 60 min, LOW mode by default.

Therapeutic logic

At the core: programmes P1–P9

Every protocol in this field combines the reference programmes P1–P9 — general homeostasis, body levels, ANS/CNS and targeted nerves — according to the clinical goal.

See programmes P1–P9 →
Limits & safety

Protocols are guidelines.

·

Parameters are guides; the therapist adapts them to the patient.

·

NESA is applied after individual assessment — as part of the overall medical plan.

·

Absolute contraindications (pacemaker, pregnancy, active electrical implants) follow the device IFU.

INDEPENDENT CONSULTING

Before you invest — the independent assessment.

We map clinical goals, workflows, budget and reimbursement — then recommend the solution that meets the department’s needs, not the easiest to sell.

Assessment & selection →
Related topicDiabetic autonomic neuropathy — the cardiovascular risk rarely discussedRead more →
NESA · Materials

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