NESA XSIGNAL® терапия в офталмологията
NESA · Ophthalmology

Calm for the eye’s fine systems.

NESA supports ophthalmic conditions linked to autonomic dysregulation, non-invasively.

Information for healthcare professionals

Self-recognition

Do you recognise yourself?

A dry eye that does not fully respond

✓dry or gritty eyes
✓burning or itching
✓vision that fluctuates
✓tears relieve only briefly
✓a foreign-body sensation
✓eyes that tire early
What happens in the autonomic nervous system

Like an irrigation system that barely drips; with a stronger parasympathetic “brake” the eye moistens better. Tear secretion is parasympathetically driven.

Self-assessment, not self-diagnosis — discuss with a professional.

NESA benefits

Non-invasive modulation of the autonomic nervous system.

01
01

Regulation

Balance of autonomic responses.

02
02

Comfort

Reduction of tension and fatigue.

03
03

Recovery

Support for recovery.

Downloads

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Mechanism, indications, protocols and clinical data for implementing NESA.

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NESA XSIGNAL® терапия в офталмологията — микротокове през крайниците
Across the four limbs

Microcurrents through the wrists and ankles — the whole autonomic axis at once.

In depth · autonomic regulation

The eye is under close autonomic control.

Pupil width, accommodation, tear-film production and ocular blood flow are regulated by sympathetic and parasympathetic input. Unbalanced autonomic regulation with sympathetic dominance can present as blurred vision, focusing problems, eye pain and changes in tear film and vascular tone. NESA addresses the autonomic regulation; many ophthalmic procedures are done on an awake patient, where the baseline autonomic state affects comfort and recovery.

Clinical fields: pre-operative anxiety (L1), acute intra-operative anxiety (L2), immediate post-operative care (L3) and dysautonomia-related visual complaints (L4 — min. 20 sessions, extendable to 30–40). Three-phase lead electrode: central (sternum, C6–C7) → metameric (C1–C2) → toward the affected zone. 60-min session, LOW; no HIGH setting is foreseen for the ophthalmic protocols.

Evidence — in context

For ophthalmology we build on NESA's general ANS evidence. The effect is mechanism-based — ANS modulation, anxiety regulation and HRV. As proof of principle:

+40%

prefrontal alpha waves (10 sessions); −30% anxiety/obsession/hostility (20 sessions) — Álvarez de los Heros, UAH 2019.

HRV

HRV (SDNN) and vagal tone (RMSSD).

Limits & safety: NESA is applied after individual medical assessment. Protocols are guidelines; they complement ophthalmic care. XSIGNAL is a medical device — applied after individual assessment. Absolute contraindications: pacemaker and pregnancy.

Protocol · 12–20 sessions · 2× weekly · 55 min

Bring NESA into your practice.

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Protocol parameters

Real values from the handbook (INF-CD-022)

Pre-operative anxiety

Sessionssingle/few
FrequencyInduction → maintenance
DurationP1 30 · P7 30–45 min
ProgrammesP1 · P7
Guiding electrodeProcessus spinosus C6–C7
QuestionnairesWeCardio · Cortisol · GAD-7

Visual disturbances in dysautonomia

Sessionsmin. 20 (up to 30–40)
FrequencyInduction → maintenance
Duration60 min
ProgrammesP1 · P2 · P7 · P8 · P9
Guiding electrodeSternum · C1–C2 · C6–C7
QuestionnairesWeCardio · GAD-7 · PSQ · PSQI

Source: NESA protocol handbook · INF-CD-022 (2025-V.1). Standard session 60 min, LOW mode by default.

Therapeutic logic

At the core: programmes P1–P9

Every protocol in this field combines the reference programmes P1–P9 — general homeostasis, body levels, ANS/CNS and targeted nerves — according to the clinical goal.

See programmes P1–P9 →
Limits & safety

Protocols are guidelines.

·

Parameters are guides; the therapist adapts them to the patient.

·

NESA is applied after individual assessment — as part of the overall medical plan.

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Absolute contraindications (pacemaker, pregnancy, active electrical implants) follow the device IFU.

INDEPENDENT CONSULTING

Before you invest — the independent assessment.

We map clinical goals, workflows, budget and reimbursement — then recommend the solution that meets the department’s needs, not the easiest to sell.

Assessment & selection →
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