NESA XSIGNAL® терапия в гериатрията
NESA · Geriatrics

Dignity, sleep and autonomic balance.

In elderly patients NESA improves sleep and autonomic balance — measurable via HRV.

Information for healthcare professionals

NESA benefits

Non-invasive modulation of the autonomic nervous system.

01
01

HRV

Significant improvement in variability.

02
02

Sleep

Better sleep quality.

03
03

Function

Support for cognitive function.

Study results
+35%
cognitive function (dementia population) — Teruel-Hernández, IJERPH 2023
+49%
sleep quality — Teruel-Hernández, IJERPH 2023
−58%
daytime sleepiness — Teruel-Hernández, IJERPH 2023
Objective basis · autonomic balance
HRV
objective marker · measured with WeCardio (reference SDNN ≈ 50 ms)
RMSSD
vagal tone · reference RMSSD ≈ 42 ms

Study results; individual results may vary. Information intended for healthcare professionals.

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Mechanism, indications, protocols and clinical data for implementing NESA.

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NESA XSIGNAL® терапия в гериатрията — микротокове през крайниците
Across the four limbs

Microcurrents through the wrists and ankles — the whole autonomic axis at once.

In depth · autonomic regulation

Not a single symptom, but the capacity for self-regulation.

With age the sympatho-vagal balance often shifts against vagal tone — the body stays in heightened activation, recovery and sleep suffer. Durable vagal tone is a marker of adaptability and resilience. NESA aims exactly at improving vagal tone and flexible autonomic regulation — a common foundation on which many age-related complaints converge. HRV makes changes traceable and allows management by the individual course.

Clinical fields: quality of life in the elderly (C1 — open count; P1, P2, P4, P5, P7, P8; electrode C6–C7, C4 or mesenteric; WeCardio, EQ-5D) and adjuvant anti-aging/longevity therapy (C4 — P1, P2, P5, P7 partly 45 min / HIGH, P8; electrode sternum, C4, mesenteric, C6–C7; WeCardio/WHOOP, actigraphy). Three phases: central → metameric → focal. 60-min session, LOW by default; in geriatrics, a gentle start with close monitoring.

Evidence — in context

For geriatrics there is early published data supporting the mechanism. This is early, supporting evidence with measurable results.

+49%

sleep quality, −58% daytime sleepiness, +35% cognitive function in dementia — Teruel-Hernández, IJERPH 2023.

HRV

objective marker of autonomic balance — measured with WeCardio before and after the protocol (reference: SDNN ≈ 50 ms).

Limits & safety: NESA is applied after individual medical assessment. Protocols are guidelines; they complement geriatric care. XSIGNAL is a medical device — applied after individual assessment. In elderly and multimorbid people — careful counselling, gradual escalation and ongoing monitoring. Absolute contraindications: pacemaker and pregnancy.

Protocol · 12–20 sessions · 2× weekly · 55 min

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Protocol parameters

Real values from the handbook (INF-CD-022)

Quality of life in older adults

Sessionsopen number
FrequencyInduction → maintenance
Duration60 min
ProgrammesP1 · P2 · P4 · P5 · P7 · P8
Guiding electrodeC6–C7 · C4 · Mesenterial
QuestionnairesWeCardio · EQ-5D

Source: NESA protocol handbook · INF-CD-022 (2025-V.1). Standard session 60 min, LOW mode by default.

Therapeutic logic

At the core: programmes P1–P9

Every protocol in this field combines the reference programmes P1–P9 — general homeostasis, body levels, ANS/CNS and targeted nerves — according to the clinical goal.

See programmes P1–P9 →
Limits & safety

Protocols are guidelines.

·

Parameters are guides; the therapist adapts them to the patient.

·

NESA is applied after individual assessment — as part of the overall medical plan.

·

Absolute contraindications (pacemaker, pregnancy, active electrical implants) follow the device IFU.

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We map clinical goals, workflows, budget and reimbursement — then recommend the solution that meets the department’s needs, not the easiest to sell.

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