Precision and calm in the dental practice.
NESA supports dental medicine in bruxism and temporomandibular dysfunction through autonomic regulation.
Information for healthcare professionals
Do you recognise yourself?
Jaw clenching and teeth grinding
Like a jaw shaped into a clenched fist. Constant stress “clenches the fist”: clenching, grinding and orofacial tension, day and night.
Self-assessment, not self-diagnosis — discuss with a professional.
Non-invasive modulation of the autonomic nervous system.
Bruxism
Reduction of muscle tension.
TMD
Support in temporomandibular dysfunction.
Calm
Lowering patient stress.
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Mechanism, indications, protocols and clinical data for implementing NESA.
Microcurrents through the wrists and ankles — the whole autonomic axis at once.
Where anxiety and tension affect the outcome.
NESA (non-invasive ANS neuromodulation, XSIGNAL) complements dental and maxillofacial care. The orofacial region is densely innervated by trigeminal afferents closely wired to autonomic and central circuits. Sustained sympathetic dominance lowers the pain threshold, intensifies muscular tension (bruxism) and delays recovery.
Clinical fields: acute intra-procedure anxiety, pre-operative anxiety, post-procedure recovery, orofacial pain, bruxism, trigeminal neuropathy (I/II), Burning-Mouth syndrome. Three-phase lead-electrode logic: central (sternum, C7) → metameric (C2/C3) → focal (complaint zone, V3 or Gasser ganglion). 60-min session, LOW; HIGH only for B8 with no response after 12 sessions.
For dentistry we build on NESA's general ANS evidence. The effect is mechanism-based — ANS modulation, anxiety regulation and HRV. As proof of principle:
prefrontal alpha waves (10 sessions); −30% anxiety/obsession/hostility (20 sessions) — Álvarez de los Heros, UAH 2019.
HRV (SDNN) and vagal tone (RMSSD).
Limits & safety: NESA is applied after individual medical/dental assessment. Protocols are guidelines. XSIGNAL is a medical device — applied after individual assessment. Absolute contraindications: pacemaker and pregnancy.
Bring NESA into your practice.
Real values from the handbook (INF-CD-022)
Central and mixed bruxism
Trigeminal neuropathy I
Source: NESA protocol handbook · INF-CD-022 (2025-V.1). Standard session 60 min, LOW mode by default.
At the core: programmes P1–P9
Every protocol in this field combines the reference programmes P1–P9 — general homeostasis, body levels, ANS/CNS and targeted nerves — according to the clinical goal.
See programmes P1–P9 →Protocols are guidelines.
Parameters are guides; the therapist adapts them to the patient.
NESA is applied after individual assessment — as part of the overall medical plan.
Absolute contraindications (pacemaker, pregnancy, active electrical implants) follow the device IFU.
Before you invest — the independent assessment.
We map clinical goals, workflows, budget and reimbursement — then recommend the solution that meets the department’s needs, not the easiest to sell.
NESA information pack
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