NESA XSIGNAL® терапия за лимфен дренаж
NESA · Lymphatic drainage

Movement and drainage in a natural rhythm.

NESA supports lymphatic drainage through non-invasive regulation of the autonomic nervous system.

Information for healthcare professionals

Self-recognition

Do you recognise yourself?

Swelling, heaviness and slow drainage

✓swelling of the legs or area
✓heaviness
✓marks from clothing or socks
✓tight skin
✓worse at the end of the day
✓slow circulation
What happens in the autonomic nervous system

Like a blocked return pipe — the water won’t drain. In oedema the autonomic tone regulates the vessels; with high “gas” venous return slows.

Self-assessment, not self-diagnosis — discuss with a professional.

NESA benefits

Non-invasive modulation of the autonomic nervous system.

01
01

Drainage

Support for lymphatic circulation.

02
02

Swelling

Aid in reducing swelling.

03
03

Recovery

Support for tissue recovery.

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Mechanism, indications, protocols and clinical data for implementing NESA.

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NESA XSIGNAL® терапия за лимфен дренаж — микротокове през крайниците
Across the four limbs

Microcurrents through the wrists and ankles — the whole autonomic axis at once.

In depth · autonomic regulation

A complement to manual drainage.

Lymphatic and vascular transport are substantially influenced by the ANS: the sympathetic system regulates vascular tone and microcirculation. NESA is used in parallel with manual lymphatic drainage — the lead electrode follows the physiological outflow path, distal→proximal, matching the direction of the manual technique.

Clinical fields: lymphoedema, synchronous with manual drainage (I3 — P7 lasting as long as the manual session; electrode moved distal→proximal along drainage zones) and upper-limb lymphoedema after mastectomy (G1 — 20–30 baseline sessions + maintenance, min. 3×/week; with extensive lymphadenectomy, more modest expectations, transparently communicated). Three phases: central (P1, C6–C7) → metameric (L3) → focal along the zones. 60-min session, LOW; no HIGH in the lymphoedema protocols.

Evidence — in context

For lymphological indications we build on NESA's general ANS evidence. Application is mechanism-based — autonomic regulation of microcirculation and vascular tone alongside manual drainage. As a general principle (not a lymphological endpoint):

+15,7%

carotid vasodilation (cross-sectional area) — Mínguez-Esteban, Front Neurosci 2025.

HRV

HRV (SDNN) and vagal tone (RMSSD).

Limits & safety: NESA is applied after individual medical assessment. Protocols are guidelines; they complement manual drainage. XSIGNAL is a medical device — applied after individual assessment. With an oncological history (common in post-mastectomy lymphoedema), application is by qualified staff within an interdisciplinary plan. Absolute contraindications: pacemaker and pregnancy.

Protocol · 12–20 sessions · 2× weekly · 55 min

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Protocol parameters

Real values from the handbook (INF-CD-022)

Lymphoedema

Sessionsmin. 10
FrequencyInduction → maintenance
Duration= the manual therapy (P7)
ProgrammesP7
Guiding electrodedrainage zones: distal → proximal
QuestionnairesWeCardio · perimetry

Lymphoedema after mastectomy

Sessions20–30 + maintenance
FrequencyInduction → maintenance
Duration60 min (P7 30–45)
ProgrammesP1 · P4 · P7
Guiding electrodeProcessus spinosus C6–C7
QuestionnairesWeCardio · EQ-5D · PSQI · VAS

Source: NESA protocol handbook · INF-CD-022 (2025-V.1). Standard session 60 min, LOW mode by default.

Therapeutic logic

At the core: programmes P1–P9

Every protocol in this field combines the reference programmes P1–P9 — general homeostasis, body levels, ANS/CNS and targeted nerves — according to the clinical goal.

See programmes P1–P9 →
Limits & safety

Protocols are guidelines.

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Parameters are guides; the therapist adapts them to the patient.

·

NESA is applied after individual assessment — as part of the overall medical plan.

·

Absolute contraindications (pacemaker, pregnancy, active electrical implants) follow the device IFU.

INDEPENDENT CONSULTING

Before you invest — the independent assessment.

We map clinical goals, workflows, budget and reimbursement — then recommend the solution that meets the department’s needs, not the easiest to sell.

Assessment & selection →
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