NESA XSIGNAL® терапия при ревматологични състояния
NESA · Rheumatology

An answer to pain — without medication.

NESA reduces pain, shortens morning stiffness and supports function in rheumatological conditions — through autonomic regulation and better microcirculation.

Self-recognition

Do you recognise yourself?

Inflammation that flares under stress

flare-ups of joint pain
inflammation and stiffness
fatigue during flare-ups
worse with stress or poor sleep
joints that flare up
morning stiffness
What happens in the autonomic nervous system

Like a defence system with an alarm set too loud. The vagus regulates inflammation (the cholinergic anti-inflammatory reflex); with low vagal tone the flare-ups ignite.

Self-assessment, not self-diagnosis — discuss with a professional.

Why NESA in rheumatology

Pain, function and recovery — through autonomic balance.

01
01

Chronic pain

Reduced pain and shorter morning stiffness — without extra medication.

02
02

Function & mobility

Support for joint mobility and daily activity in chronic conditions.

03
03

Sleep & fatigue

Better sleep and lower autoimmune fatigue — key to quality of life.

How it works

Microcurrents that calm the nervous system.

NESA applies controlled low-intensity (0.1–1 mA) low-frequency (1–15 Hz) microcurrents through eight electrodes on the four limbs and one guide electrode. The signal reaches the autonomic nervous system and restores the balance between its sympathetic and parasympathetic branches.

In rheumatological disease this balance lowers nociception and sympathetic overactivity and improves microcirculation and sleep — factors that feed pain and fatigue.

Intensity0.1–1 mA
Frequency1–15 Hz
Electrodes8 + 1 guide
TargetAutonomic balance
Indications

Where NESA finds application in rheumatology.

01Rheumatoid arthritis — as a complement
02Osteoarthritis and joint pain
03Fibromyalgia
04Ankylosing spondylitis
05Psoriatic arthritis
06Chronic inflammatory pain
07Morning stiffness
08Autoimmune fatigue
09Sleep disturbance with pain
10Raynaud’s syndrome and microcirculation
Protocol

A clear frame for the treatment course.

A typical course for rheumatological complaints. Parameters are adapted individually by the treating specialist and combined with ongoing therapy.

12–20
sessions per course
per week
55 min
per session
1–9
NESA programmes
For whom

Built for rheumatology practice.

Rheumatology clinics

Centres seeking a non-invasive complement in chronic pain.

Pain & rehabilitation centres

Multidisciplinary teams for chronic pain and function.

Physical medicine

Mobility, pain and sleep in older patients.

Downloadable materials

General NESA presentation.

Mechanism, indications, protocols and clinical data for implementing NESA in your practice.

PDF General NESA presentationBulgarian · NESA
Frequently asked questions

Short answers for professionals.

Is the therapy safe?

Yes. NESA is a non-invasive, low-intensity method with no known systemic side effects. Sessions are conducted by a trained specialist.

Does it replace primary treatment?

No. NESA complements pharmacological and physical treatment by reducing pain and improving sleep — it does not replace primary therapy.

When are the first results felt?

Many report less pain and better sleep after 4–6 sessions; the effect builds over the full course.

Are there contraindications?

Pacemakers and other active implants, pregnancy and epilepsy require prior medical assessment. When in doubt, consult the treating physician.

Related fields

Explore adjacent areas.

NESA XSIGNAL® терапия при ревматологични състояния — микротокове през крайниците
Across the four limbs

Microcurrents through the wrists and ankles — the whole autonomic axis at once.

Protocol · 12–20 sessions · 2× weekly · 55 min

Bring NESA into your practice.

Request a demonstration →
Protocol parameters

Real values from the handbook (INF-CD-022)

Rheumatoid arthritis

Sessionsinduction 30
FrequencyInduction → maintenance
Duration60 min (P7 45)
ProgrammesP1 · P2 · P3 · P4 · P5 · P7 · P8
Guiding electrodeSternum · C6–C7 · A. mesenterica sup. · T6–T8
QuestionnairesWeCardio · VAS

Fibromyalgia and the vagus nerve

Sessions~23–28 (≈1 yr)
FrequencyInduction → maintenance
Duration60 min (P7 45)
ProgrammesP1 · P2 · P7 · P8
Guiding electrodeSternum · Processus spinosus C7
QuestionnairesWeCardio · GAD-7 · PSQI · Lattinen

Source: NESA protocol handbook · INF-CD-022 (2025-V.1). Standard session 60 min, LOW mode by default.

Therapeutic logic

At the core: programmes P1–P9

Every protocol in this field combines the reference programmes P1–P9 — general homeostasis, body levels, ANS/CNS and targeted nerves — according to the clinical goal.

See programmes P1–P9 →
Limits & safety

Protocols are guidelines, not prescriptions.

·

Parameters are guides; the therapist adapts them to the patient.

·

NESA is not suitable for every patient and promises no cure.

·

Absolute contraindications (pacemaker, pregnancy, active implants) follow the device IFU.